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Human Health and Wellbeing

Disease and premature death are a major source of suffering. Treatments now potentially within reach may extend the human healthspan and improve quality of life. We aim to support tractable and cost-effective research on the world’s most burdensome diseases, including heart disease, cancer, malaria, and others. In addition to the grants listed here, Open Philanthropy Scientific Research staff advises Good Ventures on research related to Alzheimer’s disease.

Human Health and Wellbeing is one of six thematic areas within Scientific Research.

Our Work

Press 11/2018
The promise and peril of gene drives
from The Economist

Target Malaria carries the prospect of huge humanitarian gains. It’s carefully designed, supported by Open Phil and the Gates Foundation, being carried out under international scrutiny, and gaining political support and inspiring a generation of researchers.

Grant 2/2022
University of Victoria — Syphilis Diagnostic (Caroline Cameron)
$2,000,000

Open Philanthropy recommended a grant to the University of Victoria to support work led by Caroline Cameron to develop an improved diagnostic for syphilis.

Grant 12/2021
UC Davis — Malaria Gene Drive Feasibility Analysis (Greg Lanzaro) (2021)
$10,248,967

Open Philanthropy recommended a grant to UC Davis to support subsequent stages of a feasibility analysis of a potential test of gene drives for malaria control on the adjoining West African islands of São Tomé and Príncipe.

Grant 11/2021
University of Washington — Protein Design Research (David Baker)
$3,263,750

Open Philanthropy recommended a grant to the University of Washington to continue to support protein design research, led by Professor David Baker of the Institute for Protein Design.

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Grant 9/2021
Kainomyx — Antimalarial Drug (2021)
$4,000,000

Open Philanthropy recommended an investment in Kainomyx to develop and produce new drugs to treat malaria and other parasitic diseases, such as cryptosporidiosis and toxoplasmosis.

Grant 8/2021
University of Washington — Syphilis Vaccine Development (Lorenzo Giacani)
$816,063

Open Philanthropy recommended a grant to the University of Washington to support research led by Dr. Lorenzo Giacani that may facilitate the development of a vaccine against syphilis.

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