Global Health R&D

We seek to support the development of new vaccines, drugs, and other tools to improve global health.

Historically, health technologies like vaccines and drugs have saved millions of lives around the world. However, diseases primarily affecting the world’s poorest people, such as tuberculosis, malaria, diarrheal diseases, rheumatic heart disease, and sickle cell disease receive much less research and development spending relative to their health burdens than diseases affecting the wealthy. Further investments could prevent millions of deaths and illnesses caused by neglected diseases.

Open Philanthropy has supported scientific research for human health since 2016. Over time we have learned that there are many excellent opportunities in global health R&D that we could support with increased resources and specialized staff. As a result, we launched this new program in 2023, substantially increasing our total funding in the area.

The Global Health R&D team works in parallel and in collaboration with our Scientific Research team, but with a greater focus on supporting tools and treatments through the development life cycle, including those requiring early proof of concept studies, human efficacy trials or implementation research. We are interested in funding research and development for new vaccines, diagnostics, drugs, monoclonal antibodies, and vector control tools for diseases with a large global health burden, as well as efforts to make these products more affordable and accessible.